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Higgins JPT, Li T, Deeks JJ (editors)
However, in a contemporary, large, real-world study, 39% of patients receiving GLP-1 receptor agonists did not meet efficacy goals
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Phase 2 trial data (NEJM, 2023) showed promising weight reduction results, but long-term safety and cardiovascular outcomes remain under investigation in ongoing Phase 3 trials
Retatrutide is a 40-plus amino acid peptide with a molecular weight near 5 kDa
