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BMJ 347 , f5934 (2013)

Diabetes 66 (5), 12721285

Hippocampal neurogenesis: a biomarker for depression or antidepressant effects

Extensive preclinical studies have shown that incretin-based drugs can achieve significant cerebral protection and reduce neuronal loss by reducing synaptic loss and amyloid plaque load, decreasing hyperphosphorylation of proteins, and anti-inflammatory effects [54]
With the thought that GLP-1s would help resolve health disparities, differences in ability to pay may deepen existing health disparities and prevent marginalized communities from benefiting from these potentially life-changing drugs