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Description
A 2024 study in Scientific Reports found that glucagon-like peptide 1 GLP-1 drugs show a link to a significantly higher risk of depression, anxiety, and potential suicide, likely due to how the GLP-1 affects regions involved in mood and reward regulation

2019;68(Supplement 1):244-OR

Not only was energy intake during ad libitum lunch (primary endpoint) substantially lower with semaglutide vs placebo (approximately 35%), the same pattern also held true for subsequent ad libitum evening meal and evening snack box, demonstrating no compensatory effect due to a reduced lunch intake earlier in the day

This makes it critical to understand how body weight and health risks related to diabetes and heart disease change once treatment is discontinued

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