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No differences were observed in intravenous or oral steroid use, or initiation of advanced therapy

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The only difference between the 2 lies in tirzepatides ability to mimic both the GLP-1 hormone and the GIP hormone, making it a dual-action medication

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Therefore, regulatory guidance specifies that this major cardiovascular risk equivalent requires all new drugs and biologics for glycemic control to demonstrate cardiovascular safety

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Safety signals in specific populations, insufficient efficacy in certain endpoints, or manufacturing challenges could all slow progress

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