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Description
No differences were observed in intravenous or oral steroid use, or initiation of advanced therapy
The only difference between the 2 lies in tirzepatides ability to mimic both the GLP-1 hormone and the GIP hormone, making it a dual-action medication

Therefore, regulatory guidance specifies that this major cardiovascular risk equivalent requires all new drugs and biologics for glycemic control to demonstrate cardiovascular safety

Safety signals in specific populations, insufficient efficacy in certain endpoints, or manufacturing challenges could all slow progress
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