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Table of Contents How GLP-1 therapies interact with the gut Microbiome shifts and metabolic outcomes Inflammation, gut integrity, and insulin resistance Clinical implications and future research directions How GLP-1 Therapies Interact With the Gut Environment GLP-1 is not just a pancreatic hormone

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18 Once weekly semaglutide 2.4 mg resulted in 10.6% bodyweight reduction (trial product estimand) at week 68 in the STEP 2 trial