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The key finding: GLP-1 receptor agonists significantly reduce levels of Cyp2e1 a liver enzyme that normally breaks down alcohol into acetaldehyde (the toxic compound responsible for much of alcohol's liver damage)

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14 The number of fibroblasts measured by HSP47 expression were highest in exendin-4 treated mice as was the number of differentiated myofibroblasts which were characterized by the presence of Acta2+ cells by immunohistochemical analysis
