is semaglutide or tirzepatide safer vs. Semaglutide: Which Best for Weight Loss? Compounds can be very safe
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For most people, that timing gap is the most important number in this comparison
Conclusion: Not losing weight on GLP-1 drugs can be frustrating, but its important to remember that weight loss is rarely linear

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Nevertheless, as demonstrated in the STENO-2 trial, residual renal and risk and overall mortality remains high, also due to the fact that the different treatment targets are often not reached [4]

JCI Insight 2020;5:e133429.ArticlePubMedPMC 60