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In another study conducted in a rat model of metabolic syndrome, chronic treatment with liraglutide showed a greater increase in coronary vessel internal diameter than vehicle control (Sukumaran et al., 2020)

5.1 Urban-Centric Availability Most GLP-1 prescriptions and stock are concentrated in metros and Tier-1 cities where diabetologists and endocrinologists are based

This comprehensive, systems-oriented viewpoint promotes fundamental shifts towards proactive, mechanism-focused initiatives that enhance and will continue to advance our comprehension of positive, healthy aging, as outlined in Table 4, which highlights critical knowledge gaps and outlines actionable future research directions for GLP-1 RAs in promoting healthy aging

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School of Immunology and Microbial Sciences, Kings College London, London, United Kingdom