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What the best body-composition data says As more research is published, studies show that 25-40% of weight loss on GLP-1 medications can be from lean muscle mass

Figure S21

Originally prescribed to treat people with type 2 diabetes, GLP-1 drugs are now being used to treat obesity and a variety of other medical conditions

Dual agonists outperform single GLP-1 agonists for weight loss

Mood The literature regarding psychiatric adverse effects (AEs) of GLP-1 agonists is inconclusive