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Similarly, control mice with Pcsk9 overexpressioninduced atherosclerosis treated with 10 g/kg semaglutide for 18 weeks also showed reduced liver inflammation, as confirmed by quantitative PCR analysis of Col1a1 , Tnf , Ccl2 , Tgfb1 , Cd3g , Il2 , and Il4 expression (29)

It comes down to chemistry

Its reported side effects include headache, tachycardia, flushing, hypotension and urinary urgency

But first off, some rats are cute, all right

Conclusion: In subjects with obesity and high ALT, semaglutide 0.2-0.4 mg daily reduced ALT to an extent that was broadly comparable across weight loss categories, and resulted in dose-related ALT normalization in up to 46% of subjects after 52 weeks