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Laferrre B, Reilly D, Arias S, Swerdlow N, Gorroochurn P, Bawa B, Bose M, Teixeira J, Stevens RD, Wenner BR, Bain JR, Muehlbauer MJ, Haqq A, Lien L, Shah SH, Svetkey LP, Newgard CB

Twenty-five healthy subjects received PYC (150 mg/d) for 6 wk

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A recent analysis estimated that the economic burden of cancer in the United States will reach $5.3 trillion over the next three decades (61)
Similarly, the specific blocking of Gq signalling with YM254890 or transient receptor potential melastatin 5 (TRPM5) with triphenylphosphine oxide (TPPO) suppressed the triagonist-induced enhancement of GSIS
