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Common Side Effects The most commonly reported retatrutide side effects include: Nausea Vomiting Diarrhea Gastrointestinal discomfort These side effects are similar to other GLP-1 receptor agonist therapies and often appear during dose escalation periods

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12,13 As evidence of our concern about patients taking GLP-1 receptor agonists, we identified a recent case report that described a patient taking semaglutide who experienced an aspiration event with food remains during induction of anesthesia despite having fasted for 18 hours

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