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Originally developed to treat diabetes, semaglutide began making headlines in Hollywood for its remarkable weight loss benefits

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For example, in an incentive motivation task where participants exert physical strength on a handgrip to obtain food or monetary rewards, sc injection of the GLP-1 analog liraglutide prevents the increase in incentive motivation induced by hunger in participants with high, but not low, insulin sensitivity [97]

The researchers note that further analyses are planned to address some of these variables