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Overview of the Chemistry, Pharmacokinetic Profiles, and Pharmacodynamic Mechanisms of DPP4 Inhibitors DPP4is are a diverse group of small molecules that vary in their chemical structure, pharmacokinetic properties, including absorption, distribution, metabolism, and excretion pathways, and pharmacodynamic attributes, such as the potency and selectivity of DPP4 inhibition [66, 71, 72]

Teneligliptin possesses a distinctive pharmacokinetic profile characterized by a long elimination halflife of approximately 26.9 h, which enables convenient oncedaily dosing regardless of food intake

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Type 2 diabetes (34.80%) and weight loss (14.71%) emerged as the most predominant indications, while others accounted for 3.92%, and unknown or missing constituted 46.57% (Table 1)

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