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These observational studies have not identified catastrophic adverse outcomes, but evidence gaps persist

To confirm the capacity of ER36 to regulate ALDH1A1 in breast cancer cells, we visualized ER36 and found it translocated from the cell membrane and cytoplasm into the nuclei upon 4-OHT treatment of ER66 /ER36 + MDA-MB 436 cells (Figure 6C)

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