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Gastrointestinal Interoception in Eating Disorders: Charting a New Path
R., & Tuncil, Y

11 Elevated cortisol can negatively impact metabolism, promote fat storage (especially abdominal fat), disrupt other hormones involved in appetite regulation, increase cravings (particularly for high-sugar, high-fat foods), and contribute to insulin resistance, potentially hindering weight loss efforts despite medication and diet changes
Pili-like proteins of Akkermansia muciniphila modulate host immune responses and gut barrier function

However, for individuals without metabolic issues , the benefits may be less pronounced
