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Elderly patients and other special populations Older adults ( 65 years) with MASLD may experience greater gastrointestinal intolerance and dehydration risk

NICE recommend tirzepatide and semaglutide for patients with at least one weight-related comorbidity and a BMI 35 kg/m 2 (or BMI 30 kg/m 2 and who meet the criteria for referral to specialist weight management services, for semaglutide only) and liraglutide for patients with a BMI 35 kg/m 2 , non-diabetic hyperglycaemia, and a high risk of cardiovascular disease

Animals who did not receive semaglutide or antibodies received a corresponding vehicle injection on the same day as the dosed animals throughout the study

Brinkhaus, M
