glp-1 receptor agonist antipsychotic weight gain study New Loss Drugs in Psychiatry Efficacy and Safety of GLP-1

Int J Mol Sci (2023) 24(4):3140

By combining glucagon receptor activation with GLP-1 and GIP signaling, triple agonist medications aim to maximize metabolic benefits while minimizing unwanted glucose elevation

These strategies compared to currently available drug medications such as thiazolidinediones, sulphonylureas, and insulin, have the potential to treat diabetes without causing side effects of hypoglycemia and weight gain

& Buse, J

But GLP-1 drugs differ in one significant way from their natural counterpart: Unlike human-made GLP-1 hormones that appear and disappear quickly around mealtimes, artificial GLP-1 receptor agonists can stick around much longer