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How Tirzepatide Works Tirzepatide works by targeting two important metabolic receptor pathways in the body: GLP-1 (Glucagon-Like Peptide-1) GIP (Glucose-Dependent Insulinotropic Polypeptide) These receptor pathways are involved in appetite regulation, glucose signaling, digestion, and energy balance

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"The microdosing strategy has some attractive benefits, including helping to mitigate side effects and being able to customize the dose to the minimum efficacious dose for individual patients," says Katie Sorensen , a nurse practitioner specializing in GLP-1 medications who was not involved in Burgess' treatment

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