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GLP-1 agonists have already transformed the treatment landscape for diabetes and obesity, and their potential role in addiction medicine represents an exciting new frontier

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Some GLP-1 medications have demonstrated cardiovascular benefits in clinical trials (such as LEADER for liraglutide, SUSTAIN-6 for semaglutide, and REWIND for dulaglutide), and discontinuation may result in loss of these protective effects

AMPK AMP-activated protein kinase