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If you are shifting from daily to weekly medication, you can administer the medication the next day after stopping the previous medication

During exendin-4 treatment, IL- 1b was transiently increased in normoglycemic mice and decreased in hyperglycemic mice

Key features of retatrutide include: Acts as a triple agonist on GLP-1, GIP, and glucagon

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Furthermore, GLP-1-based medications such as GLP-1 receptor agonists and dipeptidyl peptidase-4 inhibitors, have been shown to improve diabetes control in preclinical and clinical trials with human subjects