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This occurs through the release of decorin, which binds to the AGER receptor on macrophages, driving immune activation (230)

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reduced sexual ability in both men and women), eye problems, such as changes or loss of vision, or gum disease associated with diabetes

One of the things where for me, the rubber really met the road with this was its one thing to talk about weight, health and to talk about the weight, health, hormones, and its another to be able to actually evaluate their function, and because they only stay on for 2 to 5 minutes, I was talking to a bunch of individuals about the research and they were like, you know, actually the research is really hard because we cant show whats happening to your own hormones