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These include: Nausea Vomiting Diarrhoea Constipation Abdominal pain These side effects are typically mild to moderate, most common when starting the medication or increasing the dose, and often subside over time

Clinical pearls -Pre-hydration with normal saline reduces nephrotoxicity -Monitor K, Mg, serum creatinine closely -If possible choose liposomal formulations

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Cardiovascular markers Both compounds showed improvements in cardiovascular risk markers in their respective trials

"GLP-1 receptor agonists in the treatment of type 2 diabetes state-of-the-art." Molecular Metabolism, vol
