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Clinical trials of GLP-1 medications show that up to about 40% of weight loss can come from lean mass, highlighting the importance of protein intake, resistance training, and overall nutrition support to help preserve muscle during weight loss

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Since AUD is a chronic and recurrent disorder, a comprehensive randomized clinical trial with ample sample size is necessary to determine the long-term efficacy of GLP-1 agonists as a treatment for this disorder

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