is semaglutide being discontinued The FDA's Decision to Ban Compounds: What You Need to Know Semaglutide Discontinuation and Its Health
Description
The longer stool sits in the colon, the more water is extracted from it resulting in harder, dryer stools that are more difficult to pass

Tirzepatide : Nausea 12-33%, diarrhea 12-21%, vomiting 5-13%

This phenomenon, dubbed the incretin effect, has been credited to two particular gut peptides, GLP-1 and GIP (67, 68)

Overall, these observations highlight the relevance of gut microbiota for overall metabolic health and suggest that treatment of T2DM and its associated complications may interact with the gut microbiota

doi: 10.1258/phleb.2007.007051
