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Under Canadas adult obesity guidelines, drug therapy is generally considered appropriate for adults with a BMI of 30 or higher, or 27 or higher with at least one weight-related condition (such as high blood pressure, type 2 diabetes, high cholesterol, or sleep apnea)

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Severe or persistent vomiting, severe abdominal pain, fainting, dehydration, confusion, or symptoms of low blood sugar need prompt medical assessment, especially after a possible dosing error

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