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Ideal Treatment For: Otherwise healthy clients with a BMI of 30 or greater

This triggers several beneficial effects: Enhanced insulin secretion from the pancreas when blood glucose levels are elevated Reduced glucagon release , which prevents the liver from producing excess glucose Slowed gastric emptying , meaning food moves more slowly from the stomach into the intestines Increased satiety signals to the brain, reducing appetite and food intake These combined mechanisms help lower blood glucose levels in people with type 2 diabetes and promote weight loss in those with obesity

Other important contributing factors are eating disorders and depression, which are more common in patients with T1D compared to the overall population ( Figure 1 Obesity increases the risk of obesity-related as well as diabetes-related complications in patients with T1D, including micro- and macrovascular complications, various types of cancer, and overall mortality ( Figure 1 )

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It increases the risk of: Type 2 diabetes MASLD (metabolic dysfunction-associated steatotic liver disease, formerly called NAFLD) Cardiovascular disease The loss of estrogen also accelerates sarcopenia, the loss of lean muscle mass, which further slows metabolism and reduces energy expenditure