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At higher doses (515 mg/kg), animal studies have shown a reduction in dopaminergic neurons in the substantia nigra and striatum, suggesting potential neurotoxicity that may impair motor and cognitive functions [141,142]

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[7] Mounjaro is currently FDA approved for type 2 diabetes, but is frequently used safely and effectively off label for weight loss in individuals without type 2 diabetes

GLP-1 receptor activation slows gastric emptying, reduces appetite, and promotes satiety

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