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The harder transitions come at the lower doses, particularly when stepping from the lowest available dose to nothing at all

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After 48 weeks of treatment, the results were: -2.1% for the placebo group, -8.7% for the 1 mg group, -17.1% for the combined 4 mg group, -22.8% for the combined 8 mg group, and -24.2% for the 12 mg group

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