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Constipation occurs in approximately 20-30% of patients using GLP-1 receptor agonists during the first months of treatment

D., Hilberg, O., Hess, S., Jensen, T

The authors explain the limitations: First, we did not measure GFR with iohexol clearance during the first weeks of the study, and the number of participants with cystatin C eGFR values was limited during the up-titration phase of the study

Similarly, patients with a pronounced metabolic phenotype, characterized by high baseline triglycerides, elevated apolipoprotein B, and poor glycemic control, might be ideal candidates, as these are parameters directly and favourably modulated by these agents [36]

They found that patients prescribed semaglutide had a significantly lower risk of Alzheimer's disease, compared to those taking seven other diabetes meds