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Description
By enhancing insulin sensitivity, GLUT4-mediated glucose uptake, and AMPK activity, GLP-1RAs improve skeletal muscle energy metabolism and reduce lipid accumulation in skeletal muscle
Future directions for research include longitudinal studies in diverse populations to further elucidate causal relationships and the exploration of novel therapeutic targets, as well as the effectiveness of healthcare models aimed at preventing the onset of one condition in individuals diagnosed with the other
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Across the STEP trial program, dose escalation demonstrated a clear dose-response relationship
