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Clinics generally advise against starting treatment for anyone who: Is pregnant Has a personal or family history of thyroid cancer Has a history of multiple endocrine neoplasia (MEN) syndrome BMI and health history serve as a useful starting point for this evaluation, not an absolute cutoff, since metabolism and overall wellness also weigh into a provider's decision

10.1016/j.jhep.2016.01.014 9

Manufacturing scale-up issues could also create delays

This is where I push back on a lot of the stacking advice youll see online