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Description
The protective effects of exenatide against AGEs-induced articular matrix degradation in human primary chondrocytes
Bergenstal RM, Wysham C, Macconell L, DURATION-2 Study Group, et al
This discussion focuses on those agents that have progressed to clinical trials, specifically TZDs and glucagon-like peptide (GLP-1) analogs
Advantage : Pemvidutide Body Composition# Pemvidutide : MOMENTUM trial showed only 21.9% of total weight loss came from lean mass, better than historical data for diet/exercise and other incretin drugs
However, its usefulness for progressed DKD and established CVD remains unclear
