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Oral semaglutide, by contrast, is taken daily on an empty stomach and requires specific administration techniques to maximize absorption, including not eating for 30 minutes after taking your dose

In major clinical trials, such as the landmark STEP 1 trial published in the New England Journal of Medicine , a once-weekly injection of semaglutide 2.4 mg resulted in an average body weight reduction of roughly 14.9% over 68 weeks