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However, molecular mechanisms of how semaglutide may restore the balance of several interlinking aspects of metabolism to exert pleiotropic effects in obesity and diabetes complications are based mainly on preclinical data, while available evidence in humans appears to be lacking

Tirzepatide is the active receptor in Mounjaro and Zepbound injections

Patients who are pregnant, planning to become pregnant, or breastfeeding should discuss alternative treatment options with a licensed provider