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Despite this reassuring human data, UK product information contains warnings and precautions regarding thyroid C-cell tumours based on rodent data

Semaglutide: product labeling advises discontinuation at least 2 months before a planned pregnancy, reflecting its long elimination time and extended exposure window (153, 157, 158)

Mounjaro is administered as a once-weekly subcutaneous injection, with doses typically starting at 2.5 mg and potentially increasing to a maximum of 15 mg depending on individual response and tolerability

Unknown whether semaglutide causes thyroid C-cell tumors, including medullary thyroid carcinoma (MTC), in humans, as human relevance has not been determined

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