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In these analyses, the only significant change relative to placebo found with GLP-1RA therapy was a reduction in triglycerides of 0.29 mmol/L (95% CI 0.57, 0.01) relative to placebo

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Because the percentage of weight loss over a short period had, in some cases, exceeded that achieved by bariatric surgery, the drug was assigned the highest weight-reduction rating among all weight-loss injections

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