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The future of NAFLD treatment seems exciting and challenging and has the potential to include more personalized and targeted therapeutic approaches, while issues concerning their safety must be thoroughly recorded and appropriately evaluated [42, 43, 138, 144146].

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This effect appears to explain the carbohydrate stimulated ileal brake where plasma GLP-1 increases without a change in PYY (64)

In that report, the incidence of pancreatic cancer was also 2.9 and 2.7 times greater with exenatide and sitagliptin, respectively, compared to other oral antidiabetic medications

Neuropsychopharmacology 42, 23872397