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Moreover, given that GLP-1 is a more potent inducer of the beta-cell GLP-1R than glucagon, alpha-cell transcriptional and functional heterogeneity, in terms of GLP-1 production, may importantly affect intra-islet paracrine interactions

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Wegovy (Semaglutide) is not for insulin-dependent diabetics (type 1 diabetes)

Bottom line Its safe to stop semaglutide at any time, so long as you do so under your healthcare providers supervision

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