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These recommendations were motivated by the results of a recent cardiovascular outcomes trial (SELECT study), performed in obese subjects without diabetes, which reported a 20% reduction in the composite endpoint of cardiovascular death, non-fatal myocardial infraction and non-fatal stroke

Andersson E, Ljtsson B, Smit F, Paxling B, Hedman E, Lindefors N, et al

This approach might suit patients with a stable or satisfactory response, good tolerability and no pressing safety, access, or cost concerns

Docusate sodium (Colace) coats the stool itself

no real-time or emergency access
