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Integrated Clinical Review Patients taking both medications benefit from coordinated care: Regular GP or specialist review (frequency determined by individual circumstances) Blood pressure monitoring Assessment of weight management progress and metabolic parameters Review of medication adherence and technique (particularly Saxenda injection technique) Evaluation of overall treatment goals and quality of life Patients should maintain open communication with their healthcare team, reporting any concerns, side effects, or changes in symptoms promptly

[1] [4] Dulaglutide (Trulicity) is licensed only for type 2 diabetes, not for weight management

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Ozempic (semaglutide) is a selective GLP-1 receptor agonist

In a phase 1b trial that included participants with T2D, administration of retatrutide led to a placebo-adjusted least-squares mean weight reduction of 8.96 kg in the 12 mg group after 12 weeks [9]