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5 Excess fat stored in adipose tissue triggers an initially local and subsequently systemic inflammatory process, which makes obesity a low-grade chronic inflammatory disease

Efficacy and Safety of Once-Weekly Semaglutide Versus Once-Daily Sitagliptin as an Add-On to Metformin, Thiazolidinediones, or Their Combination in Patients With Type 2 Diabetes (SUSTAIN 2): A 56-Week, Double-Blind, Phase 3a, Randomised Trial

Despite an inauspicious history, the pharmacologic management of obesity is at an exciting crossroad

A 2023 analysis of over 17,000 patients found that semaglutide reduced the risk of kidney disease progression by 24% compared to placebo
The relative abundance of different microbial species is known to depend on the presence of specific nutrients (389)
