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Guidelines currently recommend organ-specific management of obesity-related complications

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Suppressed macrophage infiltration followed by reduced macrophage foam cell formation by active forms of GLP-1 and GIP was demonstrated by Nagashima M, et al
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Because its a stimulant, the phentermine label warns about increases in blood pressure, insomnia if taken late in the day, and its contraindicated in people with a history of cardiovascular disease, uncontrolled hypertension, hyperthyroidism, glaucoma, agitated states, or a history of drug abuse
