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Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes In patients with preexisting cardiovascular disease and overweight or obesity but without diabetes, weekly subcutaneous semaglutide at a dose of 2.4 mg was superior to placebo in reducing the incidence of

Dual- and multi-receptor agonists may be a novel drug class to treat obesity and type 2 diabetes mellitus with high efficacy.

Additionally, weight loss medications were discussed as potential treatments for patients given the link between the disease and obesity

This expanded receptor activation explains the distinct clinical effects observed with retatrutide