is trulicity a glp 1 drug Comparing Ozempic, Wegovy and Other GLP-1 Drugs GLP-1 Medications for Weight Loss:
Description
doi: 10.1111/j.1463-1326.2012.01561.x
DPP-4 inhibitors are oral and weight-neutral but generally less potent
47 However, it is not advised during pregnancy as it is considered a class C drug, defined as a drug with established risk that cannot be ruled out
For daily administration, they would need to modify the molecule so that it would have a half-life of ~10 h instead of the 1 to 2 min half-life of the native hormone which is both degraded in plasma and rapidly filtered by the kidney
For example, companies that sell a compounded GLP-1 wont be able to claim that the product is the same as an FDA-approved drug
