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Researchers collected data on weight change for up to 72 weeks

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Cholesterol transport assays showed that GLP-1 administration improved ABCA1-dependent cholesterol efflux, leading to lower total cholesterol, either alone or in combination with miR-19b inhibitor

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219 It has been postulated that the ability of GLP-1 to enhance metabolism may decrease endoplasmic reticulum stress via increasing mitochondrial production of ATP and Ca 2+ , which could be utilised for assisting endoplasmic reticulum homeostasis