glp 1 weight loss time frame How long does it take for GLP-1 to start working: timeline from first dose to full results Study finds GLP-1 receptor agonists

Lancet 392(10157):15191529 Marso SP, Daniels GH, Brown-Frandsen K, Kristensen P, Mann JF, Nauck MA, Nissen SE, Pocock S, Poulter NR, Ravn LS, Steinberg WM, Stockner M, Zinman B, Bergenstal RM, Buse JB (2016) LEADER Steering Committee

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Renal impairment GLP-1RAs were found to be associated with acute kidney injury

This is one reason obesity is linked to higher RA disease activity, harder-to-reach remission, and lower response to treatment