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Currently under Phase 3 clinical investigation by Eli Lilly, Retatrutide is structurally and mechanistically differentiated from semaglutide, which acts as a single GLP-1 receptor agonist, and tirzepatide, a dual GIP/GLP-1 agonist

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dual and triple multi-agonists in PCOS models We next scaled down the doses of the poly-agonists in both PCOS models: 50 nmol/kg of GLP1/E and 3 nmol/kg of the dual and triple agonists, as selected according to previous references 33,34,35