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Yet once nicotine is removed, the bodys natural relaxation systems - especially melatonin and serotonin regulation - begin to function properly again, often leading to more genuine calm and deeper sleep
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Similarly, a study using a mouse model found that PNE produced hyperactivity that was associated with selective decreases in cingulate cortical volume and radial thickness and a decrease in drug-induced dopamine release in the frontal cortex [36]
