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Large-scale misinformation That being said, one of the most disconcerting aspects of the media coverage surrounding anything related to e-cigarettes is the negative, often even alarmist, tone that is used to report the latest research developments on these devices

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These detrimental effects are mediated by complex mechanisms, including direct hepatotoxicity, oxidative stress, immune dysregulation, oncogenic signaling, and systemic metabolic disturbances

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